ISO 10993-11:2017 subacute systemic toxicity injection 28-day test cost is 6000 US dollars; Huatongwei laboratory test time is 30 days; the laboratory is a third-party testing laboratory accredited by China Food and Drug Administration, welcome to consult: peifeng. email@example.com
Toxicology animal tests can be divided into four types according to the exposure period, namely: acute, subacute, subchronic and chronic toxicity tests.
The latter three can be collectively referred to as repeated exposure toxicity tests.
Acute toxicity refers to the toxic effect caused by the body (human or experimental animal) once (or multiple times within 24 hours) exposure to foreign compounds, and even death.
Chronic toxicity refers to the toxicity caused by long-term low-dose effects of chemicals on organisms, and the exposure period is ≥6 months.
Subacute toxicity means that the exposure period is not long (usually 3 months), or the exposure time is not long (several 10 days or even months) causing damage to the body's function and (or) structure. Subacute toxicity is often described in terms of toxic reaction, toxic dose, damaged target organs, non-effect level, and histopathological changes.
Subacute toxicity is a kind of toxic performance between acute toxicity and chronic toxicity, and sometimes it is difficult to draw a clear boundary.
Subchronic toxicity refers to the toxic effects of experimental animals exposed to larger doses of foreign compounds for multiple consecutive days.
Subacute systemic toxicity test standard:
ISO 10993-11, GB/T 16886.11, USP 88, GB/T 14233.2